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NYSE:PFE
Healthcare Drug Manufacturers - General

PFIZER INC

A global biopharmaceutical giant delivering innovative medicines and vaccines with a diversified portfolio spanning human health, animal health, and consumer care segments.

■ Key Metrics

Revenue
$62.58B
Net Income
$7.81B
Gross Profit
$46.51B
Operating Cash Flow
$11.70B
Total Assets
$208.16B
Shareholders' Equity
$86.78B
Long-Term Debt
$61.64B
Cash & Equiv
$1.14B

⚖ Investment Thesis

Bull Case

Investors should consider Pfizer for its attractive dividend yield supported by robust operating cash flow of $11.70B and a diversified pipeline that mitigates reliance on any single product. The stock offers value through potential share buybacks funded by excess liquidity and the strategic repositioning toward high-value oncology and immunology assets.

Bear Case

Bearish cases highlight the risk of declining sales as blockbuster vaccines lose patent exclusivity, which could compress margins given the heavy investment in general and administrative expenses of $13.79B. Additionally, the significant debt load relative to equity and potential for further M&A integration challenges pose risks to future earnings stability.

◉ About PFIZER INC

Pfizer Inc. is a global biopharmaceutical leader delivering innovative medicines and vaccines across human health, animal health, and consumer care markets. With a diverse portfolio including renowned brands like Pfizer and Comirnaty, the company serves patients worldwide while managing a significant pipeline of late-stage clinical assets. The firm operates through integrated segments focusing on immunology, oncology, virology, and rare diseases to address critical unmet medical needs.

⚙ Analysis

Management Discussion

Pfizer demonstrated resilience with $62.58B in revenue and $7.81B net profit in 2025, recovering strongly from the sharp normalization following its peak pandemic earnings in 2022. The company generated substantial free cash flow to fund $6.93B in acquisitions and maintain a healthy balance sheet with $1.20B in ending cash, though debt levels remain elevated at $61.64B.

Industry Overview

The global pharmaceutical industry is characterized by high R&D costs, strict regulatory oversight, and rapid technological shifts toward personalized medicine and gene therapies. Pfizer operates in a competitive landscape where patent cliffs are common, forcing companies to continuously innovate or acquire new assets to maintain revenue growth and market share.

☰ Financial Statements

Income Statement
Balance Sheet
Cash Flow
Metric2022202320242025
Revenue$100.33B$58.50B$63.63B$62.58B
Cost of Revenue$34.34B$24.95B$17.85B$16.07B
Gross Profit$65.99B$33.54B$45.78B$46.51B
Operating Expenses$31.26B$32.48B$37.75B$38.99B
Operating Income$34.73B$1.06B$8.02B$7.52B
G&A$13.68B$14.77B$14.73B$13.79B
Stock-Based Comp$872.0M$525.0M$877.0M$799.0M
D&A$5.06B$6.29B$7.01B$6.59B
Amortization$3.60B$4.70B$5.30B—
Other OpEx$17.58B$17.71B$23.02B$25.20B
Non-Operating Income$0$0$0$0
Interest Expense$1.24B$2.21B$3.09B$2.67B
Interest Income$251.0M$1.62B$545.0M$603.0M
Pre-Tax Income$34.73B$1.06B$8.02B$7.52B
Income Tax$3.33B$-1.11B$-28.0M$-266.0M
Continuing Ops$31.40B$2.17B$8.05B$7.79B
Discontinued Ops$6.0M$-15.0M$11.0M$25.0M
Net Income$31.41B$2.16B$8.06B$7.81B
Minority Interest$35.0M$39.0M$31.0M$41.0M
Net to Common$31.37B$2.12B$8.03B$7.77B
Metric2022202320242025
Current Assets$51.26B$43.33B$50.36B$42.90B
Cash & Equivalents$416.0M$2.85B$1.04B$1.14B
Accounts Receivable$10.95B$11.18B$11.46B$11.87B
Inventory$8.98B$10.19B$10.85B$10.65B
Other Current Assets$30.91B$19.11B$27.00B$19.23B
Long-Term Assets$145.95B$183.17B$163.04B$165.26B
PP&E (Net)$16.27B$18.94B$18.39B$19.32B
Intangibles$43.37B$64.90B$55.41B$53.73B
Goodwill$51.38B$67.78B$68.53B$71.26B
Operating Leases$3.00B$2.92B$2.29B$2.21B
LT Investments$15.07B$15.37B$2.23B—
Other LT Assets$5.82B$1.62B$15.97B$18.50B
Total Assets$197.21B$226.50B$213.40B$208.16B
Current Liabilities$42.14B$47.79B$42.99B$36.98B
Accounts Payable$6.81B$6.71B$5.63B$5.24B
Current Debt$2.56B$2.25B$3.75B$3.00B
Current Leases$620.0M$527.0M$356.0M$330.0M
Deferred Revenue$2.52B$2.70B$1.51B$784.0M
Other Current Liab$27.33B$33.23B$29.31B$25.19B
Long-Term Liabilities$59.15B$89.42B$81.90B$84.40B
Long-Term Debt$32.88B$61.54B$57.41B$61.64B
LT Operating Leases$2.60B$2.63B$2.29B$2.29B
Other LT Liab$23.67B$17.29B$19.76B$20.47B
Total Liabilities$101.29B$137.21B$124.90B$121.39B
Shareholders' Equity$95.92B$89.29B$88.50B$86.78B
Paid-In Capital$91.80B$92.63B$93.60B$94.47B
Retained Earnings$125.66B$118.35B$116.72B$114.61B
AOCI$-8.30B$-7.96B$-7.84B$-8.07B
Treasury Stock$113.97B$114.49B——
Total L&E$197.21B$226.50B$213.40B$208.16B
Metric2022202320242025
Net Income (CFO)$31.41B$2.16B$8.06B$7.81B
Non-Cash Adjustments$-4.99B$7.04B$12.58B$12.42B
Working Capital Changes$2.85B$-502.0M$-7.90B$-8.53B
Cash from Operations$29.27B$8.70B$12.74B$11.70B
Capital Expenditures$3.24B$3.91B$2.91B$2.63B
Cash from Investing$-15.78B$-32.28B$2.65B$-1.35B
Debt Issuances$0$30.83B$0$9.68B
Debt Repayments$3.30B$2.57B$2.25B$6.76B
Share Buybacks$2.00B$0$0—
Cash from Financing$-14.83B$26.07B$-17.14B$-10.30B
FX Effect$-165.0M$-40.0M$-66.0M$41.0M
Net Change in Cash$-1.51B$2.45B$-1.81B$91.0M
Beginning Cash$1.98B$468.0M$2.92B$1.11B
Ending Cash$468.0M$2.92B$1.11B$1.20B

Frequently Asked Questions

How does PFIZER INC make money?

The company's revenue is driven by four primary pillars: Vaccines (including COVID-19 products and influenza), Innovative Medicines (oncology, immunology, and virology therapies), Biologics & Biosimilars, and Consumer Health. Financials reflect strong cash generation from operations ($11.70B) supporting these segments, while significant goodwill ($71.26B) indicates a history of strategic M&A integrating diverse therapeutic areas.

What are the main risks for PFE?

Revenue concentration risk tied to the expiration of key patent protections for high-volume products like Comirnaty, potential regulatory headwinds from global health authorities, and volatility in net income driven by large one-time charges or acquisition integration costs as seen in recent years.

What is PFE's competitive advantage?

First-mover advantage in vaccine distribution networks, a robust late-stage pipeline extending beyond its COVID-19 franchise, and superior manufacturing scale that provides cost leadership in biologics production.

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Not financial advice. All content is for informational purposes only. Data may contain errors. Consult a qualified financial advisor before making investment decisions.